IFNAR1 anticorps

N° du produit ABIN2666006

L’anticorps Souris Monoclonal anti-IFNAR1 a été validé pour FACS. Il convient pour détecter IFNAR1 dans des échantillons de Souris.

Aperçu rapide pour IFNAR1 anticorps (ABIN2666006)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNAR1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: MAR1-5A3

Détail du produit anti-IFNAR1 anticorps

Marque: Ultra-LEAF™

Purification: The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Agent conservateur: Azide free

Conseil sur la manipulation: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR-1

Sujet: IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.

Pathways: Signalistation JAK/STAT, Hepatitis C